BIOS 2014 Functional Proteins and Genes
Credit Points 10
Legacy Code 300936
Coordinator Patrick O'Doherty Opens in new window
Description Biochemistry is the study of the chemistry of life. By understanding the structure and roles of biological macromolecules found in cells students will develop the concept of self assembly of these molecules to form life. Topics include the structure of carbohydrates, lipids, proteins, and nucleic acids and how they function in the lipid and aqueous environments of the cell. Basic metabolism is introduced with an overview of the major pathways in cells, mechanisms of regulation, and an introduction into important cofactors and intermediatory molecules. These concepts will be reinforced through practical classes that teach critical skills in experimental design, analysis and interpretation.
Discipline Biochemistry and Cell Biology
Student Contribution Band HECS Band 2 10cp
Check your HECS Band contribution amount via the Fees page.
Level Undergraduate Level 2 subject
Equivalent Subjects BIOS 2001 - Biochemistry 1 BIOS 2036 - Proteins and Genes
- Identify and explain biologically important chemical bonds and functional groups and describe their interaction.
- Recognise and describe the structure of monomeric units of major biomolecules in a cell.
- Explain how complex biomolecules form through polymerisation, chemical modification or aggregation of these monomeric units form complex functional or structural molecules.
- Discuss key metabolic processes, their control and cellular location.
- Relate different biomolecules to different cellular structures and processes.
- Handle biomolecules for analysis in a laboratory.
- Collect, record and analyse laboratory data in a lab book consistent with legal standards.
- Be able to perform basic biochemical calculations (mole calculations, dilutions, unit conversion, standard curve and basic enzymatic calculations).
- Work as a member of a group.
- The cell, groups of important biomolecules, bonds, Functional groups, genes to proteins
- The aqueous environment
2. Biomolecules - Lipids
- The Chemistry and structure of fatty acids
- Membranes: phospholipids and glycolipids
3. Biomolecules - Introduction to Carbohydrates and Glycobiology
- The Chemistry and nomenclature of mono, di and polysaccharides
- Heteropolysaccharides: cellulose, starch, glycogen and The extracellular matrix
4. Biomolecules - Nucleic acids
- Ribose, deoxyribose, phosphodiester bonds, bases
- structural differences between RNA and DNA
5. Biomolecules - Proteins
- Amino acids: functional groups; acid base properties; symbols
- structure of proteins: peptide bonds, protein folding, pictorial representation of protein structure
- Classification and functions of proteins
- protein Packaging and post translational modification
- protein degradation
6. Introduction to metabolism
- Overview of anabolic and catabolic pathways and their regulation
- Characteristics of enzymes: active sites; catalytic principles; Basic enzyme kinetics
- introduction to important branch Point, High energy compounds and co-Factors
7. Quantitative aspects of Biochemistry
- handling and Analysing biomolecules in A laboratory
- developing independence in data organisation, recording and calculations
- maintaining A legal Standard laboratory note book
The following table summarises the standard assessment tasks for this subject. Please note this is a guide only. Assessment tasks are regularly updated, where there is a difference your Learning Guide takes precedence.
|Final Examination||2 hours||50||Y||Individual|
|Written Assignment - research assigned protein||Max 500 words||10||N||Individual|
|Laboratory Component - (a) Laboratory Book completeness/ correctness, (b) Practical Skills Quiz||Throughout semester||20||N||Individual|
|Quiz - (a) Post-laboratory questions (online), (b) Functional Molecules Quiz||Throughout semester||20||N||Individual|
- Tymoczko, JL, Berg, JM & Stryer, L 2013, Biochemistry: a short course, 2nd edn, W.H. Freeman, New York.