BIOS 3001 Advanced Cell Biology
Credit Points 10
Legacy Code 300850
Coordinator Mark Jones Opens in new window
Description Cells of the body are studied in the context of health and disease, including mechanisms by which cells respond to the environment and integrate in and around tissue. Fundamental cellular processes are discussed that are important in embryonic development, stem cells, haematology and cancer. This subject investigates the action of hormones, growth factors and morphogens; their receptors and signalling pathways and the cellular responses they trigger. This subject covers modern techniques in cell culture, tissue engineering, advanced microscopy and other modern experimental approaches that enable dynamic understanding of live cell function.
Discipline Biochemistry and Cell Biology
Student Contribution Band HECS Band 2 10cp
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Level Undergraduate Level 3 subject
Equivalent Subjects LGYA 6014 - Mammalian Cell Biology and Biotechnology BIOS 3011 - Cell Signalling
Incompatible Subjects LGYA 5857 - Cell Signalling and Molecular Immunology
On successful completion of this subject, students should be able to:
- Describe detailed microscopic appearance of eukaryotic cells and their specialization, from stem cells to blood and tissue.
- Explain the compartmentalization of molecules and their transport throughout the cell.
- Explain the interrelationship of cells with their immediate environment including adjacent cells, the extra-cellular matrix, and the cytoskeleton.
- Describe the molecular events, regulated by receptors and signal transduction pathways, cells activate following stimulation.
- Describe the development of cells (e.g. haematopoiesis), their identification, morphology and function in the context of haematology.
- Explain the detailed microscopic characterization of eukaryotic cells in blood and tissue, including the use of confocal microscopy and fluorescence correlation spectroscopy.
- Demonstrate technical and interpretive skills for cell culturing, including cell characterization using advanced microscopy and image analysis.
The structure and function of membranes, organelles and the cell cytoskeleton.
Intracellular compartmentalization of molecules and their transport.
The interrelationship of cells with their immediate environment including adjacent cells, the extra-cellular matrix, and the cytoskeleton.
Cell communication through: Receptors - families, general properties; receptor-ligand binding studies and outcomes, and Signalling molecules - structural variety; functional classification.
Cell division including stem cells, the cell cycle, and its control and cell death.
The development of cells (e.g. haematopoiesis), their identification, morphology and function is investigated in the context of haematological and cell disorders and stem cell therapies.
The detailed microscopic characterization of eukaryotic cells in blood and tissue, including confocal microscopy and fluorescence correlation.
The development of technical and interpretative skills relevant to cell culture methods, cell characterisation through specific stains/probes, using advanced microscopy and image analysis techniques.
The following table summarises the standard assessment tasks for this subject. Please note this is a guide only. Assessment tasks are regularly updated, where there is a difference your Learning Guide takes precedence.